CMD Tissue Repository at the Medical College of Wisconsin
The CMD Tissue Repository (CMD-TR) is a place to safely store body tissues donated through routine surgery or at autopsy that can be used for research. The Repository can also bring in your left-over tissue from a previous muscle biopsy you had.
Through the Repository, we hope to bridge the gap between patients and researchers by facilitating the donation and distribution of patient tissue. Access to these tissues is critical to the progression of research and the development of treatment therapies, but the process of tissue donation can be cumbersome without someone who knows the system to help you. The staff of the CMD-TR can assist with this process, relieving you of any burden, and donated tissue will be distributed for use in research studies without the requirement for future patient involvement or any cost to you.
Why Donate Tissue to the CMD-TR?
- Human tissue is needed to test theories and treatment drugs; is the bridge between animal and clinical studies
- Results of human tissue studies can advance patient care and drug development faster
- Centralized collection, storage, and distribution of tissue to the scientists with the best ideas for treatment
- We need samples from many different people for studies
- Everyone who’s had a muscle biopsy can consent to have it transferred to the CMD-TR
- Many families are interested in organ donation options. Although many state programs cannot accept organ donations from a person having a congenital muscle disease, the CMD-TR can accept your donation.
CMD Biobank at the Coriell Institute
By creating a well characterized, central source of samples from individuals with congenital muscle disease, the CMDIR and the Coriell Institute are working together to facilitate congenital muscle disease research and invest in the future of therapies. The CMD BioBank will be housed in the National Institute of General Medical Sciences Human Genetic Cell Repository at the Coriell Institute in Camden, New Jersey. Samples in the NIGMS repository have been utilized in over 5,000 scientific publications by researchers in more than 50 countries. Click here for an overview of Coriell's biobanking services.
The CMDIR will support the CMD BioBank by identifying and facilitating sample transfers from existing collections at other institutions. To provide scientists with a de-identified data set, CMD BioBank samples will link to existing profiles in the CMDIR through a deindetifying ID number. The CMDIR staff will provide the following information to be stored with the sample: age at the time of sample donation, genetic diagnosis, maximal motor function, breathing status, and level of heart and brain involvement. Having this detailed information regarding clinical severity assists scientists using the samples in understanding therapy response.